A lesbian is reported to have given birth to her brother's child after IVF treatment.

The American woman became pregnant using eggs from an anonymous donor which were then fertilised by her brother because she wanted to have a child with some "genetic likeness" to herself and her family. The baby is now six months old.

The brother, a married man with two children, volunteered to donate sperm to help his sister to have a baby with his wife's approval. He and his wife have agreed not to disclose to anyone that the brother is the baby's father.

Doctors at the leading US infertility clinic involved in the case said they agreed to the "genuine and loving" request because the woman's mother was a Holocaust survivor and she and her brother were among the few remaining members of that family.

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The case, the first of its type reported by an infertility clinic, was published last week in a new international medical journal Reproductive Biomedicine Online, edited by the British test-tube baby pioneer Robert Edwards who said he believed such treatment should also be allowed in the UK.

In a discussion paper in the journal, Kamal Ahuja, scientific director of the Cromwell IVF clinics in Britain, says: "When you hear of this case initially, there is an inevitable yuk factor. But when you look at it in detail the case is a very moving one."

He concludes that a similar case would probably be approved in the UK as the procedure is not fundamentally different from sister to sister egg donation, which is allowed in the UK and that the birth of the baby did not constitute any form of incest or consanguinity.